Overview
Scientist (PhD), Scientific Innovation & Research Division Jobs in Toronto, ON at Custom Biologics
Full job description
Custom Biologicshas an exciting opportunity for anPhDtrained scientist to join our Scientific Innovation and Research Group in Toronto, Canada.
We are a Health Canada audited, GMP-compliant, global service provider for functional testing of biotherapeutics, biosimilars and antibody drug conjugates. For over 19 years our scientists have been designing and validating sophisticated bioanalytical assays to characterize and measure the therapeutic potential of large and small molecule biotherapeutics. Our work supports regulatory drug submission applications from biopharmaceutical companies globally.
We are seeking a Scientist with expertise in protein biochemistry, cellular biology and molecular biology. Strong troubleshooting skills and QPCR experience is highly preferred. The successful candidate will be a key technical contributor to the design, validation and execution of cell-based and solid phase ligand binding assays to measure the functional and affinity binding properties of biotherapeutics including therapeutic monoclonal antibodies, biosimilars, antibody drug conjugates, peptides, biologics and oncolytic viruses.
This position requires hands-on laboratory work, as well as supervision of research associates and technicians. Familiarity with GMP/GLP regulations is desired but not a required.
Scientific excellence is the pillar of the Company. The ideal candidate will be joining a team of highly motivated individuals and a workplace culture driven by collaboration, achievement, quality and growth. S/he is highly motivated with a strong ‘can-do’ personality, excellent laboratory, critical thinking, results driven, and works well within a team to deliver excellence to our clients.
KEY DUTIES AND RESPONSIBILITIES
Design, validate and execute in vitro experiments to characterize and measure the therapeutic and binding properties of biotherapeutics including monoclonal antibodies, antibody drug conjugates, biosimilars and biologics
Perform cell culture-based bioassays, immunological assays (i.e. ELISA), protein affinity binding studies (biolayer interferometry), DNA-based and other assays as required
Review and interpret scientific literature to learn about new techniques and applications.
Ensure that experiments, analytical methods and data meet the scientific and regulatory requirements for the intended use i.e. characterization, comparability, stability, and lot release. Familiarity with USP and FDA guidelines helpful but not required
Author, review and approve SOPs, study protocols, reports and other scientific documents
Maintain a steady grasp of new scientific developments and new technologies
Present scientific data to colleagues and clients, prepare and present external presentations and posters
Perform additional duties to support the safe and efficient operation of the laboratory and workplace
SKILLS & COMPETENCIES
Excellent interpersonal, verbal and written communication skills
A proven ability to be highly productive and successful in a high pace work environment with excellent attention to details and meticulous bench work
Competency in computer skills and familiarity with Microsoft Office programs (Word, Excel, Project, PowerPoint).
Self-motivated and comfortable working in a fast-paced environment
Willingness to champion new and existing projects
Excellent team player. Willing to support co-workers with other projects. Shares relevant information and seeks technical advice …
Title: Scientist (PhD), Scientific Innovation & Research Division
Company: Custom Biologics
Location: Toronto, ON
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